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2008-08-29 20:01:40

The meaning of citations

by Christina Pikas in Christina's LIS Rant

Research / Scholarship

What a grand post title, but actually, what I mean is slightly more like: the meaning of citations: what Garfield said he means in a bunch of articles vs. what people say he means and even worse what people do with his work, plus some commentary on a review chapter.

Today I read the whole Nicolaisen[*] article which I just browsed earlier (ok, so it's been A LOT longer than I intended). This is not a review of how to *do* citation analysis, that's included in the several ARIST chapters on bibliometrics and informetrics. Rather, this is a review of two streams of literature about...more

  • Nicolaisen J. (2007) Citation Analysis. Annual Review of Information Science and Technology, 41, 609-641.

2008-07-11 15:00:56

Positivist vs Pragmatic Classification Theory - yes, that's it

by Christina Pikas in Christina's LIS Rant

Research / Scholarship

A long strange trip - reading about citations in Ange. Chem. then tried to find reference, then got only to the TOC page, so then started browsing and ran across...

Hjørland's readers digest version of classification theory (thank you! everyone go read the whole thing, it's short and I'll wait):
Hjørland, B.(2008). Core classification theory: a reply to Szostak. JDoc 64, 333-342: DOI:10.1108/00220410810867560 find

I know next to nothing about classification theory (so Mark can help me!) - but I really hate some of Clay Shirky's throw off statements regarding LCSH a...more

  • Hjørland B. (2008) Core classification theory: A reply to szostak. Journal of Documentation, 64(3), 333-342.

2008-03-31 16:19:03

Leveraging scientific data using the power of the semantic web: Who wants to start?

by PA in Plausible Accuracy

Research / Scholarship

As much as I appreciate the mission of PLoS, I haven’t actually gotten around to covering any of their articles in this space. The other day I happened to come across one entitled “Open Access: Taking Full Advantage of the Content“, and knew that I would have to read it. In the paper, the authors echo ...more

  • Gerstein M. (2008) Open Access: Taking Full Advantage of the Content. PLoS Computational Biology, 4(3), e1000037. DOI: 10.1371/journal.pcbi.1000037

2008-03-25 17:14:20

I do read papers that don’t come out of David Baker’s Lab

by PA in Plausible Accuracy

Research / Scholarship

But not today. To be fair the paper I’ll be talking about today (from today’s issue of PNAS) inolves quite a few researchers from several institutions. In it, the researchers describe sort of a new way of “solving” protein structures, although the technique they describe really sits at the boundary of solution and prediction. In effect, ...more

  • Bax A. (2008) From the Cover: Consistent blind protein structure generation from NMR chemical shift data. Proceedings of the National Academy of Sciences, 105(12), 4685-4690. DOI: 10.1073/pnas.0800256105

2008-03-18 18:09:27

Engineering a virus: Mutating protein sidechains alters capsid stability

by PA in Plausible Accuracy

Research / Scholarship

Viruses are really interesting. We all know about them, mostly as those things that make us sick. In fact, only a very small percentage of viruses lead to illness in humans. This is a good thing, because there are lots and lots of viruses. I’ve been told that there are about 10,000,000 in a single ...more

  • Carpenter S. R. (2007) Aquatic eutrophication promotes pathogenic infection in amphibians. Proceedings of the National Academy of Sciences, 104(40), 15781-15786. DOI: 10.1073/pnas.0707763104
  • Mateu M. (2008) Manipulation of the mechanical properties of a virus by protein engineering. Proceedings of the National Academy of Sciences, 105(11), 4150-4155. DOI: 10.1073/pnas.0708017105

2008-03-13 17:17:41

Blocking the NK1 receptor: a potential path to combating alcoholism

by PA in Plausible Accuracy

Research / Scholarship

I spent the first 4 years of my graduate program working on the NK1 receptor. This is one of the very large and important family of G Protein-coupled Receptors which are a poorly understood and pharmaceutically interesting set of signaling proteins. In the March 14 issue of Science, George et al report the use of NK1 ...more

  • Heilig M. (2008) Neurokinin 1 Receptor Antagonism as a Possible Therapy for Alcoholism. Science, DOI: 10.1126/science.1153813

2008-03-07 14:26:50

Since we don’t have seminar, you get a paper review

by PA in Plausible Accuracy

Research / Scholarship

I had this masterful plan to write about today’s seminar from Dr. Tobias (UC Irvine), including a review of the professor’s work, direct quotes from lunch with him, and notes from his talk at the end of the day. Unfortunately weather has kept the speaker away, so instead I think I’ll just review a recent paper! Fortunately ...more

  • Hemminger J. C. (2008) CHEMISTRY: Getting Specific About Specific Ion Effects. Science, 319(5867), 1197-1198. DOI: 10.1126/science.1152799

2008-03-04 10:22:15

High mass protein structural technique pushed to new levels of detail

by PA in Plausible Accuracy

Research / Scholarship

When we want to determine the structure of a protein, we usually think of two methods. The most historically popular has been X-Ray crystallography (XRC), in which a very pure sample of the protein is induced (through a sort of mystical, poorly understood process) to form regular repeating arrays — crystals. These are ...more

  • Carpenter S. R. (2007) Aquatic eutrophication promotes pathogenic infection in amphibians. Proceedings of the National Academy of Sciences, 104(40), 15781-15786. DOI: 10.1073/pnas.0707763104
  • Chiu W. (2008) Backbone structure of the infectious ε15 virus capsid revealed by electron cryomicroscopy. Nature, 451(7182), 1130-1134. DOI: 10.1038/nature06665

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